If Week 1 was a sign of how the season is going to be, NFL fans are in for a wild ride.

Defending Super Bowl champs the Kansas City Chiefs (0-1) were upset by the Detroit Lions (1-0). In Week 2, they look to bounce back against Trevor Lawrence and the Jacksonville Jaguars (1-0) and it's still uncertain if they will be without Travis Kelce again. The Lions are favorites to continue their momentum against the Seattle Seahawks (0-1).

The New York Jets (1-0) pulled off a magical win over the Buffalo Bills (0-1) after Aaron Rodgers tore his Achilles on their opening drive. Jordan Whitehead picked off Josh Allen three times to help the Jets' offense en route to victory. New York is now the underdog as they take on the mighty Dallas Cowboys (1-0), who had a statement win of their own, while the Bills are favorites as they host the Las Vegas Raiders (1-0).

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Here are the NFL betting odds for Week 2, according to the BetMGM NFL odds.

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NFL Week 2 picks/predictions

  • Minnesota Vikings at Philadelphia Eagles
  • Green Bay Packers at Atlanta Falcons
  • Las Vegas Raiders at Buffalo Bills
  • Baltimore Ravens at Cincinnati Bengals
  • Seattle Seahawks at Detroit Lions
  • Indianapolis Colts at Houston Texans
  • Kansas City Chiefs at Jacksonville Jaguars
  • Chicago Bears at Tampa Bay Buccaneers
  • Los Angeles Chargers at Tennessee Titans
  • New York Giants at Arizona Cardinals
  • San Francisco 49ers at Los Angeles Rams
  • New York Jets at Dallas Cowboys
  • Washington Commanders at Denver Broncos
  • Miami Dolphins at New England Patriots
  • New Orleans Saints at Carolina Panthers
  • Cleveland Browns at Pittsburgh Steelers

NFL Week 2 point spreads

  • Minnesota Vikings (+7) at Philadelphia Eagles (-7)
  • Green Bay Packers (-1.5) at Atlanta Falcons (+1.5)
  • Las Vegas Raiders (+9.5) at Buffalo Bills (-9.5)
  • Baltimore Ravens (+3.5) at Cincinnati Bengals (-3.5)
  • Seattle Seahawks (+6) at Detroit Lions (-6)
  • Indianapolis Colts (-1.5) at Houston Texans (+1.5)
  • Kansas City Chiefs (-3) at Jacksonville Jaguars (+3)
  • Chicago Bears (+3) at Tampa Bay Buccaneers (-3)
  • Los Angeles Chargers (-3) at Tennessee Titans (+3)
  • New York Giants (-5.5) at Arizona Cardinals (+5.5)
  • San Francisco 49ers (-8.5) at Los Angeles Rams (+8.5)
  • New York Jets (+9.5) at Dallas Cowboys (-9.5)
  • Washington Commanders (+3.5) at Denver Broncos (-3.5)
  • Miami Dolphins (-2.5) at New England Patriots (+2.5)
  • New Orleans Saints (-3.5) at Carolina Panthers (+3.5)
  • Cleveland Browns (-2.5) at Pittsburgh Steelers (+2.5)

NFL Week 2 moneylines

  • Minnesota Vikings (+240) at Philadelphia Eagles (-300)
  • Green Bay Packers (-120) at Atlanta Falcons (+100)
  • Las Vegas Raiders (+333) at Buffalo Bills (-450)
  • Baltimore Ravens (+145) at Cincinnati Bengals (-175)
  • Seattle Seahawks (+195) at Detroit Lions (-250)
  • Indianapolis Colts (-125) at Houston Texans (+105)
  • Kansas City Chiefs (-160) at Jacksonville Jaguars (+135)
  • Chicago Bears (+135) at Tampa Bay Buccaneers (-160)
  • Los Angeles Chargers (-175) at Tennessee Titans (+145)
  • New York Giants (-250) at Arizona Cardinals (+200)
  • San Francisco 49ers (-350) at Los Angeles Rams (+260)
  • New York Jets (+350) at Dallas Cowboys (-450)
  • Washington Commanders (+155) at Denver Broncos (-190)
  • Miami Dolphins (-135) at New England Patriots (+115)
  • New Orleans Saints (-175) at Carolina Panthers (+145)
  • Cleveland Browns (-130) at Pittsburgh Steelers (+110)

NFL Week 2 over/under

  • Minnesota Vikings at Philadelphia Eagles: 48
  • Green Bay Packers at Atlanta Falcons: 40.5
  • Las Vegas Raiders at Buffalo Bills: 47
  • Baltimore Ravens at Cincinnati Bengals: 46.5
  • Seattle Seahawks at Detroit Lions: 47
  • Indianapolis Colts at Houston Texans: 40
  • Kansas City Chiefs at Jacksonville Jaguars: 51
  • Chicago Bears at Tampa Bay Buccaneers: 41.5
  • Los Angeles Chargers at Tennessee Titans: 45
  • New York Giants at Arizona Cardinals: 40
  • San Francisco 49ers at Los Angeles Rams: 44.5
  • New York Jets at Dallas Cowboys: 39.5
  • Washington Commanders at Denver Broncos: 39.5
  • Miami Dolphins at New England Patriots: 46.5
  • New Orleans Saints at Carolina Panthers: 40.5
  • Cleveland Browns at Pittsburgh Steelers: 39.5

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