After the NFL trade deadline, several teams are eager to see how their moves paid off in Week 10, which opens Thursday with the Chicago Bears (2-7) hosting the Carolina Panthers (1-7).

Chase Young said he already feels a difference in mentality with his new team, the San Francisco 49ers (5-3), who seek to snap a three-game losing streak against the Jacksonville Jaguars (6-2). The NFC West co-leaders are favored in the road game.

Joshua Dobbs shocked the world by leading the Minnesota Vikings (5-4) to a win and now takes on the New Orleans Saints (5-4). Veteran quarterback Derek Carr is slightly favored to beat the newbie.

Over at Dobbs' old team, Kyler Murray is expected to make his first start 11 months after tearing his ACL. The Arizona Cardinals (1-8) were shutout last week and seek redemption against the Atlanta Falcons (4-5).

Week 10 closes out with the Buffalo Bills (5-4) hosting the Denver Broncos (3-5), who are fresh off their bye week and a statement win.

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The Kansas City Chiefs (7-2), Los Angeles Rams (3-6), Miami Dolphins (6-3) and Philadelphia Eagles (8-1) have their byes this week.

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Here are the NFL betting odds for Week 10, according to the BetMGM NFL odds.

NFL Week 10 picks, predictions and odds

  • Carolina Panthers at Chicago Bears
  • Indianapolis Colts at New England Patriots
  • Cleveland Browns at Baltimore Ravens
  • Houston Texans at Cincinnati Bengals
  • San Francisco 49ers at Jacksonville Jaguars
  • New Orleans Saints at Minnesota Vikings
  • Green Bay Packers at Pittsburgh Steelers
  • Tennessee Titans at Tampa Bay Buccaneers
  • Atlanta Falcons at Arizona Cardinals
  • Detroit Lions at Los Angeles Chargers
  • New York Giants at Dallas Cowboys
  • Washington Commanders at Seattle Seahawks
  • New York Jets at Las Vegas Raiders
  • Denver Broncos at Buffalo Bills

NFL Week 10 point spreads

  • Carolina Panthers (+4) at Chicago Bears (-4)
  • Indianapolis Colts (-1.5) at New England Patriots (+1.5)
  • Cleveland Browns (+6) at Baltimore Ravens (-6)
  • Houston Texans (+7) at Cincinnati Bengals (-7)
  • San Francisco 49ers (-3) at Jacksonville Jaguars (+3)
  • New Orleans Saints (-2.5) at Minnesota Vikings (+2.5)
  • Green Bay Packers (+3.5) at Pittsburgh Steelers (-3.5)
  • Tennessee Titans (+1) at Tampa Bay Buccaneers (-1)
  • Atlanta Falcons (-1.5) at Arizona Cardinals (+1.5)
  • Detroit Lions (-3) at Los Angeles Chargers (+3)
  • New York Giants (+16.5) at Dallas Cowboys (-16.5)
  • Washington Commanders (+6.5) at Seattle Seahawks (-6.5)
  • New York Jets (-1) at Las Vegas Raiders (+1)
  • Denver Broncos (+7.5) at Buffalo Bills (-7.5)

NFL Week 10 moneylines

  • Carolina Panthers (+165) at Chicago Bears (-200)
  • Indianapolis Colts (-120) at New England Patriots (+100)
  • Cleveland Browns (+200) at Baltimore Ravens (-250)
  • Houston Texans (+240) at Cincinnati Bengals (-300)
  • San Francisco 49ers (-160) at Jacksonville Jaguars (+135)
  • New Orleans Saints (-135) at Minnesota Vikings (+115)
  • Green Bay Packers (+145) at Pittsburgh Steelers (-175)
  • Tennessee Titans (-105) at Tampa Bay Buccaneers (-115)
  • Atlanta Falcons (-120) at Arizona Cardinals (+100)
  • Detroit Lions (-155) at Los Angeles Chargers (+130)
  • New York Giants (+800) at Dallas Cowboys (-1400)
  • Washington Commanders (+220) at Seattle Seahawks (-275)
  • New York Jets (-120) at Las Vegas Raiders (+100)
  • Denver Broncos (+290) at Buffalo Bills (-375)

NFL Week 10 over/under

  • Carolina Panthers at Chicago Bears: 39
  • Indianapolis Colts at New England Patriots: 43.5
  • Cleveland Browns at Baltimore Ravens: 38
  • Houston Texans at Cincinnati Bengals: 48
  • San Francisco 49ers at Jacksonville Jaguars: 46
  • New Orleans Saints at Minnesota Vikings: 41
  • Green Bay Packers at Pittsburgh Steelers: 39
  • Tennessee Titans at Tampa Bay Buccaneers: 38
  • Atlanta Falcons at Arizona Cardinals: 43
  • Detroit Lions at Los Angeles Chargers: 48.5
  • New York Giants at Dallas Cowboys: 38.5
  • Washington Commanders at Seattle Seahawks: 45.5
  • New York Jets at Las Vegas Raiders: 36
  • Denver Broncos at Buffalo Bills: 47

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